Islanders aged under 40 are being told to wait for a GP's invitation, before making an appointment for their Covid-19 vaccination.
It comes after some were turned away from the Riverside Centre.
When 38 and 39 year olds were called first called forward by the government last week, people booking appointments online were only offered slots at the mass vaccination centre, on Newport Quay.
However one person who contacted the County Press was turned away from their appointment, because the Oxford AstraZeneca jab is not being administered to that age group and is the only vaccine available at the centre
The Riverside Centre in Newport is an Oxford AstraZeneca hub.
There are problems with storing the alternative Pfizer vaccine in the community, so it is only available at specific locations.
Alison Smith, Managing Director for Hampshire, Southampton and Isle of Wight CCG, said: "We are following the national JCVI guidelines when offering COVID-19 vaccinations to people on the Isle of Wight.
"At the moment the guidance for people aged 40 and under is to be offered an alternative to Oxford AstraZeneca.
"The Pfizer vaccine is available via our GP-led sites and so people aged 40 and under are advised to wait for an invitation to come through from their practice."
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